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Uncertainty of Measurement

How reliable is my patient’s result?

Measurement of uncertainty refers to the extent of variation of results at a given value within our assays. This can be affected by a multitude of factors. We generate data over an extended period of time for each of our quantitative assays in order to provide a measure of the expected range in results.

This aids the clinician to determine the significance of any change in concentration of a given analyte – particularly relevant for those tests used in monitoring.

Summary tables below contain uncertainty of measurement values for our assays.

  • Automated serology – includes total IgE, allergen specific IgE, IgA & IgG TTG (coeliac serology), CCP antibodies, MPO/PR3 antibodies, GBM antibodies, dsDNA antibodies, ENA antibodies (screen & identities), IgG Aspergillus antibodies, tryptase.
  • Neuroimmunology – includes acetylcholine receptor antibodies, MAG antibodies, GAD antibodies (Stiff Person Syndrome).
  • Immunochemistry – includes functional antibodies, intrinsic factor, GAD antibodies (diabetic serology), serum free light chains, C1 inhibitor (quantitation).
  • Complement function – includes C1 inhibitor function, classical complement function, alternative complement function.
  • Flow cytometry – including lymphocyte subsets analysis for CD3+ CD4+/CD8+ T cells, CD19+ B cells and CD16/56+ NK cells (percentages and absolute counts)

Please contact the laboratory to discuss if required.